Welcome on the Renal Fibrosis Lab website.

RF Lab is based in Rangueil University Hospital, Toulouse. We are part of the French National Institut of Health (INSERM). If you cannot come to see us you will find on this site all the information on our activity.

For any further information feel free to contact us!

World Kidney Day 2013!

WKD_2013

Today marks the eighth annual World Kidney Day! This is a very special day aimed at raising awareness of the importance of our kidneys to our overall health and to reduce the frequency and impact of kidney disease and its associated health problems worldwide.

Click on the World Kidney Day website (www.worldkidneyday.org) and share what is happening in your community.

EuRenOmics kick-off in the legendary Camp Nou stadium in Barcelona!

eurenomicsInternational experts will explain the latest cutting-edge approaches to medical research in the rare disease field at a press conference to celebrate the launch of 38 million EUR of funding for rare disease research and therapy development. This is an opportunity to meet the scientists, clinicians, patient representatives and policymakers involved in driving the advances in rare disease research and find out about the key collaborations being established through a new global initiative. Leaders in the field will explain how research and next-generation technologies aim to improve diagnosis and develop new therapies for patients with rare diseases. The press conference and Q&A will be followed by an exclusive tour of Camp Nou.

See or download the entire press statement.

A meeting with all the contributors will then take place in Sitges, Spain.

New publications from the RF-lab over summer…

Should SIX2 be routinely tested in patients with isolated congenital abnormalities of kidneys and/or urinary tract (CAKUT)?

A comparison between MALDI-MS and CE-MS data for biomarker assessment in chronic kidney diseases.

Implementation of proteomic biomarkers: making it work.

Check it out!

KUPKB Network Visualization!

After the interface allowing queries to the KUPKB, the knowledge base containing several omics data on the kidney and urinary pathways, we have developed a visualization interface allowing you to visualize relationships among molecules stored in the KUPKB, as well as visualize the stored expression of genes/proteins/miRNAs across several kidney and urinary locations/diseases. You can access is through KUPKB main page (www.kupkb.org) and just type your molecules in the search area (several types are allowed). A step-by-step process allows you then to add KUPKB data (gene/protein/miRNA expression in several kidney locations/diseases) as well as related GO terms, KEGG pathways and miRNAs that target the connected molecules.

Upcoming Events: RF-Lab in 49th ERA-EDTA Congress, Paris 2012!

Various members of the RF-Lab will attending the next ERA-EDTA congress in Paris from May 24 to 27. Four abstracts of the RF-lab were accepted for presentation (2 free communications and  2 posters):

Cécile Caubet (Poster): LC-MS/MS and antibody-array based urinary proteome analysis of obstructive nephropathy.

Romain Dissard (Poster): Renal tubular fluid shear stress facilitates monocyte activation towards inflammatory macrophages.

Julie Klein (free communication): Identification of Prognostic Markers of Post-Natal Renal Function in Bilateral Obstructive Nephropathy by Foetal Urine Proteome Analysis.

Stanislas Fager (free communication): Development and validation of a prediction score for genetic testing in HNF1B-related disease.

New Publication!

 

Renal tubular fluid shear stress facilitates monocyte activation towards inflammatory macrophages.

 

Χαιρετίσματα από την Ελλάδα!!! (Greetings from Greece)

Julie Klein and Joost Schanstra attended to the last COST EuroKUP meeting in Sounion (Greece, www.eurokup.org ) from March 29 to April 1, 2012. Julie presented the latest data on biomarkers of posterior urethral valves and Julie and Joost demonstrated the use of the KUPKB (www.kupkb.org)

World Kidney Day 2012

Today is the World Kidney Day! The 2012 Campaign will focus on the positive outcome of kidney transplantation and the life-saving aspect of organ donation.

Today, Joost will give a lecture at the IPBS of Toulouse about: “Proteomics and biomarker discovery in biological fluids: the example of obstructive nephropathy in the newborn.

New Publication!

The KUPKB: a novel Web application to access multiomics data on kidney disease.

An award for the KupKB!

The iKUP browser (www.kupkb.com) has won the 1st prize at the Ontologies Come of Age challenge (Simon Jupp, 10th International Semantic Web Conference).