Joost-Peter Schanstra


PhD, Director of research, Group leader


Road walked on:
Joost Schanstra received his PhD in Biochemistry from the University of Groningen, Groningen, The Netherlands, in 1996. From 1996 to 1999 he worked as a post-doctoral fellow in the field of Nephrology and was recruited as a Principal investigator at INSERM, Toulouse, in 1999. Since 2008, Joost Schanstra is a Director of research at the Renal Fibrosis Lab, INSERM U1048.

Main domains of expertise:
Clinical proteomics, Chronic kidney disease, Systems biology, Urinary biomarkers

Selected Publications:
Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides. Schanstra JP, Zürbig P, Alkhalaf A, Argiles A, Bakker SJ, Beige J, Bilo HJ,Chatzikyrkou C, Dakna M, Dawson J, Delles C, Haller H, Haubitz M, Husi H,Jankowski J, Jerums G, Kleefstra N, Kuznetsova T, Maahs DM, Menne J, Mullen W,Ortiz A, Persson F, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Siwy J,Snell-Bergeon J, Spasovski G, Staessen JA, Vlahou A, Mischak H, Vanholder R. J Am Soc Nephrol. 2015. [Read]

Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves (PUV). Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B, Stalmach A, Mullen W, Mischak H, Bandin F, Monsarrat B, Bascands JL, Decramer S, Schanstra JP. Sci Transl Med. 2013 Aug 14;5(198):198ra106. [Read]

Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Decramer S, Wittke S, Mischak H, Zürbig P, Walden M, Bouissou F, Bascands JL, Schanstra JP. Nat Med. 2006 Apr;12(4):398-400. [Read]

In vivo bradykinin B2 receptor activation reduces renal fibrosis. Schanstra JP, Neau E, Drogoz P, Arevalo Gomez MA, Lopez Novoa JM, Calise D, Pecher C, Bader M, Girolami JP, Bascands JL. J Clin Invest. 2002 Aug;110(3):371-9. [Read]

Kinetics of halide release of haloalkane dehalogenase: evidence for a slow conformational change. Schanstra JP, Janssen DB. Biochemistry. 1996 May 7;35(18):5624-32. [Read]