Julie Klein


PhD, Researcher, Principal investigator



Road walked on:
Julie Klein received her PhD from the University Paul Sabatier, Toulouse, France, in 2009. From 2009 to 2014 she worked as a post-doctoral fellow in the field of proteomics and bioinformatics in chronic kidney disease and was recruited as a researcher at the Renal Fibrosis Lab, INSERM U1048, Toulouse in 2014.

Main domains of expertise:
Bioinformatics tools and databases (KUPKB, Proteasix), Clinical proteomics, Cardiovascular complications of chronic kidney disease, Mechanisms of chronic kidney disease, Urinary biomarkers

Selected Publications:
New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis. Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés A, Vanholder R, Vlahou A, Klein J. Nephrol Dial Tranplant. 2015. [Read]

Urinary proteomics and molecular determinants of chronic kidney disease: possible link to proteases. Filip S, Pontillo C, Peter Schanstra J, Vlahou A, Mischak H, Klein J. Expert Rev Proteomics. 2014 Oct;11(5):535-48. doi: 10.1586/14789450.2014.926224. Epub 2014 Jun 24. [Read]

Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves (PUV). Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B, Stalmach A, Mullen W, Mischak H, Bandin F, Monsarrat B, Bascands JL, Decramer S, Schanstra JP. Sci Transl Med. 2013 Aug 14;5(198):198ra106. doi: 10.1126/scitranslmed.3005807. [Read]

Proteasix: a tool for automated and large-scale prediction of proteases involved in naturally-occurring peptide generation. Klein J, Eales J, Zurbig P, Vlahou T, Mischak H, Stevens R. Proteomics, 2013 Apr;13(7):1077-82. doi: 10.1002/pmic.201200493. Epub 2013 Feb 26. [Read]

The KUPKB: a novel Web application to access multiomics data on kidney disease. Klein J, Jupp S, Moulos P, Fernandez M, Buffin-Meyer B, Casemayou A, Chaaya R, Charonis A, Bascands JL, Stevens R, Schanstra JP. FASEB J. 2012 May;26(5):2145-53. doi: 10.1096/fj.11-194381. Epub 2012 Feb 17. [Read]