In a project driven by Inserm and the CHU of Toulouse, Bénédicte presented in Lille a novel approach to improve the management of fetuses with developmental renal disease. Using clinical proteomics focusing on amniotic fluid peptides, she showed that high definition, omics based, medicine allows accurate prediction of postnatal renal survival in developmental renal disease, not attainable by the currently available clinical workup. The study was performed in a specifically designed observational prospective multicenter cohort of 178 patients with bilateral CAKUT, the largest prospective cohort ever in this rare disease. This amniotic fluid peptide signature was independently validated in hold-out sets, in geographically different settings,Read More →
On september 20 Julie Klein presented an excellent update on the pathophysiology of diabetic kidney disease in the town of Carcassonne close the world famous “Cité”. This included the presentation of our original approach to humanise the readout of drug testing in animal diabetic models (see here for the link or here for the paper).
Valérie got her PhD degree!!! Another PhD from the RF-lab. Valerie obtained her PhD after defending her thesis entitled “Identification of biomarkers using omics-approaches for the early detection of chronic kidney disease and its complications”. In the evening this was celebrated in down-town Toulouse in the Glastag restaurant. Congratulatons Valerie and good luck for the next steps!
Ana, who will start her PhD on the CaReSyAn project (https://www.caresyan.eu/) in September in the lab gave here first scientific pitch at the CaReSyAn summer school in the Lufthansa conference center in Frankfurt. She also presented a poster on her futur project. We are aiming at a very succesful PhD project! …and welcome Ana to the RF-lab
Again this year we had the annual FR-lab BBQ. As you can see we had a full table! We even had a special guest, our former RF-lab boss, Jean-Loup Bascands no doing his research in La Reunion.
Again this year the RF-lab received high school students in their laboratory. The operation “Destination Labo” gives annual opportunity for school to come discover the world of biomedical research and exchange with researchers, engineers and technicians on their job in order to refine their career plans and encourage vocations. A window on the usually impenetrable places! On May 25, 2018, the highschool students learned about the kidney, they have been looking at cells and they determined the protein concentration in urine ! Here some snapshots:
CaReSyAn (CArdioREnal SYndrome ANalysis) will train young scientists to combat cardiovascular burden in chronic kidney disease by providing them with excellent scientific, technological and complementary skills to generate innovative insights in the pathology of the cardiorenal syndrome, and translate these into innovative clinical products. Ultimately, this will improve diagnosis as well as therapy of the cardiorenal syndrome and reduce the socio-economic burden of this disease. Patients with chronic kidney disease (CKD) exhibit a massively increased risk for cardiovascular events: 50% of patients with CKD stage 4-5 suffer from cardiovascular disease (CVD), and cardiovascular mortality accounts for ~40-50% of all deaths in patients with CKD stage 4 as wellRead More →
Valérie participates in the “My thesis in 180 seconds” contest. Check it out (in French, may be she will do a English version ..?) here: Excellent job Valérie!
The RF-lab tradition was again honored at the end of 2017 with the classical Xmas dinner. This year we decided to first engage in massive physical exercise: bowling!!! After such physical activity we enjoyed (and deserved!) the excellent Christmas dinner. During the dinner presents brought by Santa were exchanged! Happy 2018 !! Ps, check out the movie:
Congrats and well done ! When will we open the bottle ?