The Toulouse region has decided to build a cable car (in the air) to connect the Paul Sabatier University – The CHU Rangueil Hospital – The Oncopole (Cancer institute). See here for details: https://tisseo-collectivites.fr/projets/teleo We have first class seats to follow the construction of one of the 4 pillars.  

The RF-lab is back, in situ, in the lab. Masks in the corridors and labs and less persons/office, a small price to pay. Good to be back !

Due the the progression of the coronavirus in France in the middle of March 2020, the RF-lab, naturally, also had to close its doors to participate to the effort of reducing the impact of the virus.   Day-2: Sunday March 15 – the first signs Mail from Inserm’s director: “We will be closing the labs tomorrow”. A WhatsApp group of the RF-lab was generated to keep contact.   Day-1: Monday March 16 – the day before Didi and Joost were allowed to come to the lab to prepare the lockdown and bring the different “tools”  (computers and stuff) to the home of the lab members.Read More →

Congratulations Ana for winning the best poster prize during the last annual CaReSyAn meeting and Cardiorenal Winter School. Ana’s reaction to winning the prize “Last week I had the opportunity to present at the CaReSyAn annual meeting and Cardiorenal Winter School of the graduate schools SFB TRR219 IRTG & Marie-Curie ITNs CaReSyAn and INTRICARE in Frankfurt. It was a great experience and I was luckily awarded with the prize for best scientific poster presentation, which I would like to share with my supervisors Julie Klein and Joost Schanstra for all their support. But most importantly, we had the chance to listen to very interesting topics aboutRead More →

One of the aims of the RF-lab is to make the general public aware of kidney disease and its complications. Therefore every we participate to events for the general public to increase awareness. This year again we showed up at the Researchers’s night: a great succes with many children/adults visiting the stand and learning and playing how the kidney works. Follow us on twitter: RFLab.tlse.      

It has finally happened. The famous RF-lab cleaning day ! Before:                   After !                         Some prehistorical findings:                   These are CDs kids!!…what ?????   And the lab rules after cleaning up, very important !!!!  

-Cytosolic PLA2-targeting drug reduces vascular calcification-  Endothelial dysfunction is a hallmark of cardiovascular disease (CVD) that ultimately leads to thrombosis and vascular occlusion. Despite being a leading cause of death worldwide, there has been a paucity of promising drug targets to prevent and/or minimize CVD. Joost Schanstra, Trang Luong, Manousos Makridakis, Sophie Van Linthout and colleagues evaluated the arterial proteome of patients with advanced and early CVD to identify a CVD-associated signature with potential to be targeted by bioactive small molecules. Of the candidate drugs, cytosolic phospholipase A2 (cPLA2) inhibitor AACOCF3 was a top candidate to reverse in-silico the proteomic signature of advanced CVD, asRead More →